The new HALO® PCS C18

The HALO^® PCS C18 is a new phase with a positively charged surface. It has been developed to deliver improved peak shapes for basic compounds. The PCS C18 phase maintains peak symmetry at higher loading capacities and offers alternate selectivity to standard C18 phases when using mobile phases of low ionic strength.

Available with pore sizes 90 Å for small molecules and 160 Å for peptides.

The advantages of the HALO^® PCS C18

• high lot-to-lot reproducibility
• excellent stability

Your profits when using the HALO^® PCS C18

• Increased sample load with basic compounds in comparison to fully porous C18 columns
• Higher resolution, improved tailing factor and more plates in comparison to competitors’ SPP C18+ columns
• Improved peak shape and resolution for peptide in comparison to other C18 phases

Ideal applications:

• Reversed phase separations of basic analytes prone to peak tailing
• Separation of beta blockers such as Atenolol, Pindolol, Nadolol, Metoprolol, etc.
• Fast separation of basic antidepressants such as Nortriptyline, Amitriptyline, Trimipramine, etc,
• Higher resolution and higher sample load for peptides
• Peptide mapping

Further information and application examples

HALO 90 Å PCS C18 Compared to Competitor SPP Charged Surface Phase

Separation of Antidepressants Using HALO 90 Å PCS C18

Beta Blockers Separation on HALO® PCS C18

HALO 160 Å PCS C18 Rapid Peptide Separation

HALO 160 Å PCS C18 vs. C18 Peptide Panel

HALO 160 Å PCS C18 Loading Studies

order information

order information