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HALO® 1.5 - a new dimension in Chromatography
Increase the performance of your UHPLC system with the new HALO® 1.5 columns.
More sensitivity
- increased signal in comparison to columns with ID 2.1 mm
- higher efficiencies in comparison to columns with ID 1.0 mm
Higher ionization efficiency
- higher intensity in MS detection due to reduced flow rate and smaller peaks
Reduced solvent consumption
- the smaller ID leads to lower optimal flow rates without sacrificing speed
Easy to implement microflow solution
The new 1.5 mm ID columns with 2.7 µm Fused-Core material are available for the analysis of small molecules as well as bio molecules.
More Sensitivity
Increased detector signal response from UHPLC and LCMS systems.
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>2x peak area in comparison to 2.1 mm ID columns and larger
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higher efficiencies in comparison to 1.0 mm ID columns on UHPLC systems
Comparison of New 1.5 mm vs 2.1 mm ID for OTC Cough & Cold Medicines
Stability
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Stability testing delivers RSD’s <0.3% with no loss in efficiency or retention
Stability of 1000 Injections on HALO 90 Å C18 in 1.5 mm ID
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high lot to lot reproducibility
Reduced solvent consumption
- reduced internal diameter leads to lower optimal flow rates reducing solvent consumption
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decreased solvent waste removal costs
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less environmental impact
Peptide Map Solvent Savings Using HALO 160 Å ES-C18 in 1.5 mm ID
How to further optimize the system
Refer to the HALO® 1.5 Brochure from page 10 for more detailed information
- The smaller the internal diameter of the column the higher the pre- and post column impact of extra column dispersion on the result.
- Therefore extra attention should be paid to connectors and capillaries. AMT recommends MarvelXACT® finger-tight fittings and capillaries to minimize band broadening.
